A new generation of
nucleic-acid vaccines

Ascendra Therapeutics is a privately held, clinical-stage biopharmaceutical company headquartered in San Francisco.

Ascendra is developing off-the-shelf plasmid DNA and personalized mRNA vaccines to treat cancer and autoimmune disease. Led by a team of seasoned drug developers, oncologists and immunologists, we are building a modular platform designed for multiple tumor antigens and scalable manufacturing.

Vaccines that teach the immune system to fight disease

Ascendra is advancing off-the-shelf plasmid DNA and personalized mRNA vaccines designed to direct the body's own immune response against cancer and autoimmune disease.

  • Modular platform — one plasmid backbone, distinct antigen constructs for each indication
  • Broad reach across gastric, breast and ovarian cancer, plus autoimmune disease
  • Experienced leadership spanning oncology, immunobiology and drug development
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