One modular platform. Multiple tumor antigens. Scalable manufacturing.

Off-the-Shelf Plasmid DNA Vaccines

Ready-made, standardized plasmid DNA constructs that encode tumor antigens. Each indication uses a distinct antigen-encoding construct on the same circular plasmid backbone, enabling rapid development and scalable manufacturing.

  • Standardized, ready-to-administer product
  • Modular: swap antigen genes per indication
  • Intramuscular administration

Personalized mRNA Vaccines

Individualized mRNA vaccines designed around the specific antigen profile of each patient, directing a precise immune response against disease — in cancer and in autoimmune conditions.

  • Patient-specific antigen selection
  • Applications in oncology & autoimmunity
  • Complements the off-the-shelf DNA platform

How the plasmid DNA cancer vaccine works

From a ready-made DNA construct to an antigen-specific immune attack on cancer cells, in five steps.

  1. Circular double-stranded plasmid DNA with a tumor antigen gene, promoter and plasmid backbone
    1

    Plasmid DNA Construct

    A circular, double-stranded plasmid carries a tumor antigen gene and promoter on a plasmid backbone.

    Ready-made DNA construct
  2. Vial labelled Plasmid DNA Cancer Vaccine (off-the-shelf) with a syringe
    2

    Standardized Vaccine Product

    The construct is formulated as an off-the-shelf, standardized vaccine.

    Off-the-shelf
  3. Intramuscular injection into the upper arm
    3

    Administration

    The vaccine is delivered by intramuscular injection.

    Intramuscular injection
  4. Plasmid DNA enters the cell nucleus; transcription to mRNA and translation to antigen protein
    4

    Cellular Expression & Antigen Processing

    Plasmid DNA enters the nucleus, is transcribed to mRNA and translated into antigen protein.

    DNA → mRNA → Antigen
  5. Dendritic cell presents antigen fragments, activating T cells that destroy a cancer cell
    5

    Antigen-Specific Immune Response

    Dendritic cells present antigen fragments, activating T cells that target and destroy cancer cells.

    Cancer cell destruction

Modular platform — different antigen constructs for each indication

Plasmid construct and stomach
Gastric cancer
HER2

Distinct antigen-encoding construct

Plasmid construct and breast
Breast cancer
HER2

Distinct antigen-encoding construct

Plasmid construct and ovaries
Ovarian cancer
Selected tumor antigens

Distinct antigen-encoding construct

Conceptual mechanism illustration; investigational platform, not an approved cancer treatment.